Do you know the origin of the word "epigoricous"? Can you provide the definition of "plasmyotic"? These are only two of the questions Etymologic won't ask you, because I made those words up. But it will ask you a variety of questions about words, their meaning, and where they came from. It claims to be the toughest word game on the Web. I can't say whether that's true, but I did score 7 out of 10. Make of that what you will.
Etymologic [Official Site]